Kiwi cancer drug rescued

A promising lung cancer drug born of Daffodil Day funding has been rescued by a new American sponsor after a potentially disastrous finding of “unacceptable toxicity” in some patients.

Called TH-4000, the drug was invented by Dr Adam Patterson and Dr Jeff Smaill of the Auckland Cancer Society Research Centre and the Maurice Wilkins Centre at Auckland University. It becomes active only in the hypoxic parts of tumours, the zones without oxygen.

In development for a decade, the drug previously known as PR610 was first commercialised by the university in a deal with companies in Japan and the United States.

Read more